On your f 150 there is really only a couple of things that can be causing the issue with the drivers door lock to intermittently work and i have seen both of them over a dozen times so you have to have the lock not working to start with and remove the door panel.
Ford f150 driver door lock not working.
Key fob and manual door locks stopped working.
Drivers door not functioning the issue on my 2002 f250 is that my drivers door lock does not lock.
Then unplug the lock actuator in the drivers door.
Checked the batteries in the key fobs checked the fuses checked the car battery.
Ford f150 lariat door lock problem.
2012 f150 wiring harness issue.
So you could have a problem with the vsm which you said you already ruled out a wiring issue or multiple bad lock actuators unlikely especially if you have a four door model.
The automatic door locks do not work.
The vehicle security module vsm operates the door lock actuators in response to input from the door lock switches and key fob.
The remote unlocks all of the doors just fine but when i get into the truck and drive a few seconds all of the doors lock except the drivers door.
Read that it might be an actuator problem not sure i can fix this.
I have a 2013 f150 the rear passenger door has locked the lock knob is up as if unlocked but door will not open so i am not sure how to even fix it.
Is that the most logical thing or is there something else i can try first.
This means that the interior lights stay on.
I posted a video a.
Average failure mileage is 5 350 miles.
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Get the power probe here http amzn to 1kgdbew we are back with the answer on why sam s 2012 f150 4x4 wouldn t unlock at the door switch.